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目的观察在牙周基础治疗上给予盐酸米诺环素软膏局部用药治疗慢性牙周炎的临床疗效。方法选择收治的42例慢性牙周炎患者为研究对象,每位病例同一口腔内左右两侧有2个病情相似的患牙作自身对照,分别分入对照组和观察组,对照组仅给予牙周洁治及根面平整基础治疗,观察组在对照组基础上于牙周袋内注入盐酸米诺环素软膏,观察两组治疗后疗效。结果两组治疗4周后,对照组总有效率为69.05%,观察组总有效率为97.62%,观察组疗效显著优于对照组(P<0.05);两组治疗后牙周袋探诊深度(PD)、牙龈出血指数(SBI)、附着丧失(AL)及探诊出血指数(BOP)较基线水平有明显改善,且观察组改善程度显著优于对照组(P<0.05)。结论在牙周基础治疗基础上,盐酸米诺环素软膏局部用药可提高患者的疗效,有效改善牙周炎症状,促进损伤组织的愈合,值得推广应用。
Objective To observe the clinical effect of local administration of minocycline hydrochloride ointment on periodontal basis for the treatment of chronic periodontitis. Methods Forty-two patients with chronic periodontitis were selected as study subjects. Two patients with similar disease in the same oral cavity in each case were assigned to control group and observation group. The control group was given teeth only Zhou Jie and root formation of the basic treatment, the observation group in the control group on the basis of the periodontal pockets were injected with minocycline hydrochloride ointment to observe the efficacy of the two groups after treatment. Results After 4 weeks of treatment, the total effective rate of the control group was 69.05%, and the total effective rate of the observation group was 97.62%. The observation group was significantly better than the control group (P <0.05) PD, Gingival Bleeding Index (SBI), Attachment Loss (AL) and Probe Bleeding Index (BOP) were significantly improved compared with the baseline, and the improvement in the observation group was significantly better than that in the control group (P <0.05). Conclusion On the basis of periodontal treatment, local administration of minocycline hydrochloride ointment can improve the curative effect of patients, effectively improve the symptoms of periodontitis and promote the healing of damaged tissues, which is worth popularizing and applying.