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目的:分析肾活检资料的地域、种族特点,为肾脏疾病的特异性诊治提供依据。方法:回顾性分析新疆医科大学第一附属医院1148例肾活检病例的临床资料,进行统计学分析。结果:原发性肾小球肾炎占76.1%,其常见病理类型为非IgA肾病、IgA肾病;继发性肾小球肾炎占13.0%,其中以狼疮性肾炎最为常见;各病理类型分布在维吾尔族与汉族之间均无显著统计学差异(P>0.05)。原发性肾小球肾炎男性多发(男∶女=1.17∶1),而继发性肾小球肾炎以女性为主(男∶女=0.56∶1),性别分布差异有统计学意义(P<0.05)。在发病年龄统计中,原发性肾小球肾炎中维族高发年龄段为20～29岁,汉族高发年龄在30～39岁,高发年龄差异有统计学意义(P<0.05)。结论:原发性肾小球肾炎是本地区最常见的肾小球疾病,男性多发,其中以非IgA沉积型系膜增生性肾小球肾炎最为常见;继发性肾小球肾炎女性多发,狼疮性肾炎最常见;原发性肾小球肾炎中,维吾尔族比汉族患者发病年龄提前。
OBJECTIVE: To analyze the geographical and ethnic characteristics of renal biopsy data and provide the basis for the specific diagnosis and treatment of renal diseases. Methods: The clinical data of 1148 renal biopsy cases in the First Affiliated Hospital of Xinjiang Medical University were analyzed retrospectively for statistical analysis. Results: The primary glomerulonephritis accounted for 76.1%. The common pathological types were non-IgA nephropathy and IgA nephropathy. Secondary glomerulonephritis accounted for 13.0%, of which lupus nephritis was the most common. The pathological types were distributed in Uighur There was no significant difference between ethnic group and Han nationality (P> 0.05). The incidence of primary glomerulonephritis in men (male: female = 1.17: 1) and secondary glomerulonephritis in women (male: female = 0.56: 1) showed statistically significant differences in gender distribution (P <0.05). In the incidence of age statistics, primary glomerulonephritis Uighurs high incidence age range of 20 to 29 years old, Han high incidence in the age of 30 to 39 years, high incidence of age difference was statistically significant (P <0.05). Conclusion: Primary glomerulonephritis is the most common glomerular disease in the region, with multiple men, of which non-IgA deposition mesangial proliferative glomerulonephritis is the most common; secondary glomerulonephritis in women with multiple, The most common lupus nephritis; primary glomerulonephritis, Uygur Han patients earlier than the age of onset.