论文部分内容阅读
目的:评价99m Tc-MIBI脑肿瘤阳性显像及MRI诊断胶质瘤术后残留复发的价值。方法:30例胶质瘤术后患者,经病理活检或临床随访证实为术后残留复发者21例,无残留复发者9例,所有患者行99mTcMIBI SPECT脑肿瘤阳性显像及MRI平扫或增强,分析两种方法的诊断效能。结果 :99mTc-MIBI脑显像诊断胶质瘤术后残留复发的灵敏度低于MRI检查(81.0%vs.90.5%,χ2=0.006 4,P=0.035),但特异性明显高于MRI检查(88.9%vs.77.8%,χ2=3.827,P=0.006)。两者诊断胶质瘤术后残留复发的准确性无明显差异(χ2=2.149,P=0.153)。99mTc-MIBI脑肿瘤阳性显像与MRI联合诊断胶质瘤术后残留复发的灵敏度、特异性及准确性分别为95.2%、100%、93.3%,两者联合应用明显提高了诊断的准确性。结论:99mTc-MIBI脑肿瘤阳性显像诊断胶质瘤术后残留复发有较高的特异性,与MRI联合应用可明显提高诊断的准确性,具有较高的临床价值。
Objective: To evaluate the value of 99m Tc-MIBI brain tumor imaging and MRI in the diagnosis of residual tumor recurrence after glioma surgery. Methods: Thirty patients with glioma were confirmed by pathological biopsy or clinical follow-up. Twenty-one patients had residual recurrence after operation, and 9 patients had no residual recurrence. All patients underwent 99mTcMIBI SPECT brain tumor positive imaging and MRI plain scan or enhanced , Analyze the diagnostic efficacy of the two methods. Results: The sensitivity of 99mTc-MIBI brain imaging in detecting residual recurrence of gliomas was lower than that of MRI (81.0% vs.90.5%, χ2 = 0.006 4, P = 0.035), but the specificity was significantly higher than that of MRI % vs.77.8%, χ2 = 3.827, P = 0.006). There was no significant difference between the two methods in diagnosing glioma residual recurrence (χ2 = 2.149, P = 0.153). The sensitivity, specificity and accuracy of 99mTc-MIBI brain tumor imaging and MRI in the diagnosis of postoperative residual recurrence of glioma were 95.2%, 100% and 93.3% respectively. The combination of 99mTc-MIBI brain tumor imaging and MRI significantly improved the diagnostic accuracy. Conclusion: 99mTc-MIBI brain tumor positive imaging diagnosis of glioma residual recurrence has a high specificity, combined with MRI can significantly improve the diagnostic accuracy, with high clinical value.