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目的了解短程不完全间歇化疗方案治疗初治涂阳肺结核治疗效果。方法在全省选取19个县作为试点县,随机抽取200例初治涂阳病人,应用2HRZE/4H3R3方案,使用抗结核板式组合药,采用不住院全程督导管理。结果初治涂阳肺结核200例,化疗2月末、3月末痰菌阴转率分别为95%和97.5%;完成治疗率96.5%;治愈率95.5%。结论 2HRZE/4H3R3方案治疗初治涂阳肺结核安全、有效、经济、使用方便,适合在全省推广使用。
Objective To understand the short-range incomplete intermittent chemotherapy regimen for treatment of initial smear-positive pulmonary tuberculosis. Methods Nineteen counties were selected as the pilot counties in our province. 200 cases of newly diagnosed smear positive patients were randomly selected. The scheme of 2HRZE / 4H3R3 was used. The antituberculosis drug combination was used. Results The initial treatment of smear-positive pulmonary tuberculosis in 200 cases of chemotherapy at the end of February, the end of March sputum negative conversion rates were 95% and 97.5%; complete treatment rate of 96.5%; cure rate of 95.5%. Conclusions The 2HRZE / 4H3R3 regimen is safe, effective, economical and easy to use for the treatment of newly diagnosed smear-positive pulmonary tuberculosis. It is suitable for popularization in the province.