目的全面了解北京市朝阳区食品、公共场所服务业从业人员丙氨酸氨基转移酶(ALT)异常的发病情况,为有效控制和预防甲型病毒性肝炎和戊型病毒性肝炎的流行与传播,制定相关传染病传播策略提供依据。方法对2010年3月-2012年12月在朝阳区疾病预防控制中心小关体检中心办理健康证的从业人员进行体检ALT数据分析。采用SPSS 17.0统计软件进行数据处理,计量资料用率表示,用χ2检验。P<0.05为差异有统计学意义。结果 2010年3月-2012年12月共调查健康体检的从业人员136 947人次;单纯性ALT异常(≥40U/L)检出5118人次,检出率3.74%。行业之间有显著性差异,食品卫生行业的检出率明显高于公共场所(食品卫生行业占73.3%,公共场所占26.7%);属地之间也有显著性差异,外地人群高于本地人群(外地人群占57.7%,本地人群占42.3%);各年龄组之间也有显著性差异,尤其以21~40岁青壮年单纯ALT异常检出率较高;年度之间无显著性差异。结论加大宣传力度,使食品生产经营单位和每一名从业人员为了自己和人民群众的身体健康,坚持每年一次的健康体检。对ALT≥40U/L人群进一步进行甲型病毒性肝炎和戊型病毒性肝炎检测。 Objective To understand the incidence of abnormal alanine aminotransferase (ALT) in food and public service enterprises in Chaoyang District, Beijing. To effectively control and prevent the spread and spread of hepatitis A and hepatitis E, Provide a basis for the development of related infectious disease transmission strategies. Methods From March 2010 to December 2012, practitioners who took health certificates from the Center for Disease Control and Prevention in Chaoyang District Center for Disease Control and Prevention conducted physical examination ALT data analysis. Using SPSS 17.0 statistical software for data processing, measurement data utilization expressed with χ2 test. P <0.05 for the difference was statistically significant. Results From March 2010 to December 2012, a total of 136 947 health workers were surveyed; 5118 were diagnosed by simple ALT abnormality (≥40U / L), with a detection rate of 3.74%. There were significant differences among industries. The detection rate of the food hygiene industry was significantly higher than that of public places (73.3% in the food hygiene industry and 26.7% in public places); there was also a significant difference between the territories, with the population in the field higher than the local population 57.7% were from the outside world and 42.3% from the local population). There was also a significant difference among all age groups. In particular, the detection rate of simple ALT in young adults aged 21-40 years was higher than that in other years. There was no significant difference between the years. Conclusion Increasing publicity so that the food production and management units and every practitioner insist on an annual physical examination for their own health and the people’s health. ALT ≥ 40U / L population further hepatitis A and hepatitis E virus testing.