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B因子(BF)是补体旁路激活途径中的一个重要成份。我们测定血清BF、C_2、C_4浓度及CH_(50)活性,试图根据两条途径补体成份量的变化,了解体内补体活化的方式与程度。观察BF浓度在小儿急性肾炎中的变化,有助于疾病的诊断、治疗和病因探讨。
Factor B (BF) is an important component of complement pathway activation. We measured the concentration of serum BF, C_2, C_4 and the activity of CH_ (50), and tried to understand the way and degree of complement activation in vivo according to the changes of complement components in two ways. To observe the changes of BF concentration in children with acute nephritis is helpful to the diagnosis, treatment and etiology of the disease.