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目的 :探讨促使卵泡发育的经济有效的方法。方法 :选择在我中心就诊查因后诊断为排卵障碍的不孕症患者 180人 ,随机分为 3组 :A组于月经来潮第 5天口服克罗米酚 (CC) 5 0mg/d ,共 5d ;B组于月经周期第 4天开始 ,每日肌注尿促性腺激素 (HMG)75U ,据情况调整用量 ;C组于月经周期第 3天每日口服克罗米酚 5 0mg ,连用 5d ,月经周期第 5天始每日肌注HMG 75U ,据情况调整用量 ;观察比较HMG的用量、卵泡发育情况、未破裂卵泡黄素化综合征 (LUFS)、卵巢过度刺激综合征 (OHSS)、妊娠率、流产率等。结果 :克罗米酚联合尿促性腺激素促排卵治疗具有HMG用药量小、LUFS率低、排卵率及妊娠率高的特点。结论 :克罗米酚联合尿促性腺激素是促排卵方案中既经济又有效的方法
Objective: To explore a cost-effective method to promote follicular development. Methods: One hundred and eighty infertility patients who were diagnosed as having ovulation disorder at our center were randomly divided into three groups: Group A received 50 mg / day clomiphene citrate (CC) on day 5 of menstrual cramps 5d; Group B started on the fourth day of the menstrual cycle, daily intramuscular urinary gonadotropin (HMG) 75U, according to adjust the amount of the situation; C group on the 3rd day of the menstrual cycle daily oral clomiphene 50mg, 5d , The first five days of the menstrual cycle, the daily intramuscular injection of HMG 75U, according to the circumstances to adjust the amount of observation and comparison of the amount of HMG, follicular development, unruptured follicular luteinizing syndrome (LUFS), ovarian hyperstimulation syndrome (OHSS), pregnancy rate , Abortion rate and so on. Results: Clomiphene combined with urinary gonadotropin ovulation therapy has the characteristics of low dosage of HMG, low LUFS rate, high ovulation rate and pregnancy rate. Conclusions: Clomiphene in combination with urinary gonadotropin is an economical and effective method for ovulation induction