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目的:探讨老年2型糖尿病患者下肢血管变的形态学特点。方法:采用彩色多普勒超声检测100例老年2型糖尿病患者(老年组)和87例非老年2型糖尿病患者(对照组)的下肢动脉,记录病程、糖尿病肾病(DN)、糖尿病视网模病变(DR)、冠心病(DHD)、脑血管病变(CVD),测血压、身高、体重,检测血生化标准。结果:老年组下肢血管病变检出率(93.0%)明显高于对照组(73.56%),P<0.01;下肢血管内膜-中层厚度增加检出率老年组(56.87%)明显高于对照组(29.12%),P<0.01;内膜-中层厚度增加,两组均呈节段性,其中老年组(42.52%)及对照组(40.13%)呈非均匀性;非同心圆性改变,组间比较差别无统计学意义。结论:老年2型糖尿病下肢血管病变发生率高,近半数为非均匀性、非同心圆性改变。
Objective: To investigate the morphological characteristics of lower extremity vascular changes in elderly type 2 diabetic patients. Methods: The lower extremity arteries of 100 elderly patients with type 2 diabetes mellitus (elderly group) and 87 non-elderly type 2 diabetic patients (control group) were examined by color Doppler ultrasonography. The course of disease, diabetic nephropathy (DN), diabetic retinopathy Lesions (DR), coronary heart disease (DHD), cerebrovascular disease (CVD), blood pressure, height, weight, and blood biochemistry were measured. Results: The detection rate of lower extremity vascular disease (93.0%) in elderly group was significantly higher than that in control group (73.56%), P <0.01. The detection rate of lower extremity intima-media thickness was significantly higher in elderly group (56.87%) than in control group (29.12%), P <0.01; intima-media thickness increased, both groups were segmental, of which the elderly group (42.52%) and the control group (40.13%) were non-uniform; There was no significant difference between the two groups. Conclusion: The incidence of lower extremity vascular disease in elderly type 2 diabetes is high, with nearly half of them being non-uniform and non-concentric.