论文部分内容阅读
目的研究一氧化碳中毒(ACOP)患者血液中C反应蛋白(CRP)、白细胞(WBC)、中性粒细胞(N)的变化及其临床意义。方法根据患者入院时中毒的程度分为轻度中毒组、中度中毒组、重度中毒组和健康对照组。ACOP患者入院的第1天、3天、5天抽静脉血检测。结果入院的第1天、第3天,中度中毒组和重度中毒组血液CRP、WBC、N水平均显著高于健康对照组(P<0.05)。第5天,中度中毒组CRP、WBC、N水平与健康对照组比较差异无显著性(P>0.05),而重度中毒组血液CRP、WBC、N仍显著高于健康对照组(P<0.01),轻度中毒组与健康组的比较,除入院第1天血液WBC、N有显著差异(P<0.01)外,其余差异均无显著性(P>0.05)。重度中毒组第1天、第3天、第5天CRP、WBC、N水平与中度中毒组相对应天数比较差异均有显著性(P<0.05)。结论ACOP患者血液CRP、WBC、N水平的升高与中毒的程度及组织损伤的病理过程相一致,呈正相关,可作为ACOP患者诊疗的重要参考指标。
Objective To study the changes of blood C-reactive protein (CRP), white blood cells (WBC) and neutrophils (N) in patients with carbon monoxide poisoning (ACOP) and its clinical significance. Methods According to the degree of poisoning on admission, patients were divided into mild poisoning group, moderate poisoning group, severe poisoning group and healthy control group. ACOP patients admitted to the first day, 3 days, 5 days pumping venous blood test. Results On the first day and the third day after admission, the blood levels of CRP, WBC and N in moderate poisoning group and severe poisoning group were significantly higher than those in healthy control group (P <0.05). The levels of CRP, WBC and N in moderate poisoning group were not significantly different from those in healthy control group (P> 0.05), while those in severe poisoning group were significantly higher than those in healthy control group (P <0.01) ). There was no significant difference between the mild poisoning group and the healthy group except for the blood WBC and N on the first day after admission (P <0.01). There were significant differences in the days of CRP, WBC and N between the severe poisoning group and the moderate poisoning group on the first, third and fifth day (P <0.05). Conclusion The blood levels of CRP, WBC and N in ACOP patients are consistent with the degree of poisoning and the histopathological process of tissue injury, which may be used as an important reference for the diagnosis and treatment of ACOP.