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参附注射液iv给药 ,对低温冷冻和高温环境所致小鼠死亡均有显著保护作用 ,可明显推迟死亡时间 ;对正常小鼠及异丙肾上腺素负荷小鼠均可显著增强其耐缺氧能力 ;还可增强断头小鼠呼吸停止时间 ;此外 ,对HAC所致小鼠扭体反应及二甲苯所致正常及去肾上腺小鼠耳部炎症均有显著抑制作用 ,但对去肾上腺小鼠的抗炎作用减弱 ,上述结果表明参附液有一定的增强机体非特异性抵抗力作用 ,此作用的部分机理是通过肾上腺而产生
Shenfu injection iv administration has a significant protective effect on mouse death caused by low temperature freezing and high temperature environment, and can significantly delay the time of death; both normal mice and isoproterenol-loaded mice can significantly increase their resistance to deficiency. Oxygen capacity; can also increase the duration of respiratory arrest in decapitated mice; In addition, it has a significant inhibitory effect on the writhing response of mice induced by HAC and xylene-induced normal and adrenal gland ear inflammation, but it is less effective for the adrenal glands. The anti-inflammation effect of rats is weakened. The above results show that Shenfu liquid has a certain role in enhancing the body’s non-specific resistance. Part of the mechanism of this effect is through the adrenal glands.