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本文综述急性缺血性中风溶栓治疗的历史与现状。评述了非纤维蛋白选择性溶栓剂尿激酶、链激酶及纤维蛋白选择性溶栓剂组织型纤维蛋白溶酶原激活剂、单链尿激酶型纤维蛋白溶酶原激活剂的溶栓特性。评价了静脉内滴注及选择性动脉内注射治疗急性缺血性中风的临床疗效及其并发症、适应证。
This article reviews the history and current status of acute ischemic stroke thrombolytic therapy. The thrombolytic properties of tissue-type plasminogen activator, single-chain urokinase-type plasminogen activator, non-fibrin selective thrombolytic agents urokinase, streptokinase and fibrin selective thrombolytic agents were reviewed. Evaluation of intravenous infusion and selective intra-arterial injection of acute ischemic stroke clinical efficacy and complications, indications.