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对 37例中、重度妊高征孕妇、56例同龄正常孕妇和 4 0例健康非孕妇女的血清钙 (Ca)、磷(P)、碱性磷酸酶 (AKP)、甲状旁腺素 (PTH)和降钙素 (CT)的含量进行了测定并做了比较。发现妊高征孕妇的血清Ca和CT的均值较正常孕妇明显降低 (均为P <0 .0 5) ;而血清AKP和PTH明显升高 (均为P <0 .0 1) ;提示妊高征孕妇钙代谢异常。笔者还从钙代谢方面探讨了妊高征的发病机理 ,为补钙预防妊高征提供了实验依据。
Serum calcium (Ca), phosphorus (P), alkaline phosphatase (AKP) and parathyroid hormone (PTH) were detected in 37 cases of moderate and severe PIH, 56 cases of normal pregnant women of same age and 40 healthy non-pregnant women, ) And calcitonin (CT) were measured and compared. The mean serum Ca and CT levels of pregnant women with PIH were significantly lower than those of normal pregnant women (all P <0.05), while the serum AKP and PTH were significantly increased (all P <0.01) Pregnant women with abnormal calcium metabolism. The author also discussed the pathogenesis of PIH from the aspect of calcium metabolism, which provided experimental evidence for calcium prevention and treatment of PIH.