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该文报道了1例无家族精神病史患者服用异烟肼后诱发精神分裂症的情况。多数学者认为其原因是“竞争抑制”引起B族维生素缺乏,特别是烟酸和维生素B6,提示有精神病家族史的患者在使用异烟肼时应高度引起注意。
This article reports on a case of schizophrenia induced by isoniazid in one patient with no family history of psychosis. Most scholars believe that the reason is that “competitive inhibition ” causes a lack of B vitamins, especially niacin and vitamin B6, suggesting that patients with a family history of psychosis should be highly aware of the use of isoniazid.