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TRH为体内广泛分布的一种三肽物质。与其它药物一样,静脉输入TRH能产生某些副作用,最常见有恶心、面部潮红,特殊的味觉、胸闷和尿急。曾报道有一过性的血压升高,但除了在德国有少量研究报道外,均未提供有关血压增高平均值和范围的资料。此文论述了多数甲状腺机能正常的患者对静脉输入TRH后血压的反应。 实验分两组进行研究。第Ⅰ组为15名临床观察
TRH is widely distributed in the body of a tripeptide material. As with other drugs, intravenous infusion of TRH produces certain side effects, most commonly nausea, flushing, special taste, tightness in the chest and urgency. There was a transient increase in blood pressure reported, but no data were available on the mean and extent of BP increase except for a few studies in Germany. This article discusses the response of most patients with normal thyroid function to intravenous infusion of TRH. The experiment was divided into two groups to study. The first group of 15 clinical observations