我们自1984年开始用血卟啉衍生物-激光即光动力学疗法(Photodynamic ther-apy,简称PDT)治疗白色角化病与粘膜白斑,现报告如下。临床资料患者共10例,其中女性7例,男性3例,年龄自15～67岁,平均46.6岁。血尿常规,肝功能化验正常,B超检查正常。胸片除1例左肺有钙化灶外余均正常。8例为白色角化病,2例粘膜白斑,其中1例粘膜白斑已癌变为鳞状细胞癌。 We have been treating keratoses and leukoplakia with photodynamic ther-apy (PDT) since 1984, as reported below. There were 10 patients with clinical data, including 7 females and 3 males, aged from 15 to 67 years, with an average of 46.6 years. Hematuria, liver function tests were normal, B-ultrasound was normal. Chest radiographs were normal except for one case of calcification in the left lung. 8 cases were white keratoses and 2 cases of leukoplakia, of which 1 case had leukoplakia which turned cancerous into squamous cell carcinoma.