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本文对54例COPD伴或不伴肺心病者的心房肽(ANP)含量进行了测定,发现伴肺心病者组ANP含量较正常组及单纯COPD组明显为高,且与其不同心功能状态密切相关。还发现血浆ANP水平与右房压、肺动脉压存在明显相关(r分别为0.48,0.51,P<0.05)。结果提示:COPD伴肺心病者血浆ANP含量明显升高,可能与水钠潴留及肺动脉高压所致的右心容量和压力负荷增加有关。
In this paper, 54 cases of COPD with or without pulmonary heart disease in patients with atrial natriuretic peptide (ANP) content was measured and found that patients with pulmonary heart disease ANP levels were significantly higher than the normal group and simple COPD group, and its different cardiac function is closely related . Also found that plasma ANP levels and right atrial pressure, pulmonary arterial pressure were significantly correlated (r = 0.48,0.51, P <0.05). The results suggest that plasma ANP levels in COPD patients with pulmonary heart disease are significantly increased, which may be related to the increase of right ventricular volume and pressure load caused by Shuinazhuluo and pulmonary hypertension.