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循环多形核白细胞(PMN)的异质性有较多报导,根据细胞表面IgE Fc受体的表达,PMN可分为两种功能不同的亚群,机体正常状态下,80%循环PMN可与IgE—包被的绵羊红细胞形成玫瑰花结。形成花结的白细胞(RFN)具有较强的粘附性、集聚作用及对C5a的趋化作用,也具有较强吞噬作用和杀菌作用。RFN的这些特殊功能可能即其参与脓肿形成或无菌性炎症反应的原因。这些细胞在肉芽肿边缘
According to the expression of IgE Fc receptors on the cell surface, PMN can be divided into two subgroups with different functions. Under normal conditions, 80% of circulating PMNs can be combined with IgE-coated sheep erythrocytes form rosettes. The formation of floral node white blood cells (RFN) has strong adhesion, aggregation and chemotaxis to C5a, but also has strong phagocytosis and bactericidal effect. These special features of RFNs may account for their involvement in abscess formation or aseptic inflammation. These cells are on the edge of granulomas