帕金森病(PD)临床上较为常见,共14～80％患者将发生痴呆。主要表现为全面的认知功能障碍。本文应用P300地形图方法对30例原发性PD病人认知功能进行了检测,并就认知电位颅顶空间分布特点及影响P_3波改变的某些因素进行分析探讨。 资料及方法 一、研究对象及分组 1.PD组:选择30例住院病人,均按全国锥体外系疾病会议标准确诊为原发性PD。其中男23例,女7 Parkinson’s disease (PD) clinically more common, a total of 14 to 80% of patients will develop dementia. Mainly manifested as a comprehensive cognitive dysfunction. In this paper, P300 topography was used to detect the cognitive function of 30 patients with primary PD. The spatial distribution of cognitive potential and the factors influencing the change of P_3 wave were also discussed. Materials and Methods 1. Subjects and groups 1. PD group: 30 inpatients were selected and all were diagnosed as primary PD according to the National Conference on Extrapyramidal Diseases. Including 23 males and 7 females