传统抗组胺药的主要缺点是大多有中枢抑制的副作用。第二代抗组胺药主要是为了克服这一副作用而产生的。但它们仍有一些副作用,有些还是比较严重的,应引起重视。中枢抑制作用第二代抗组胺药大多具有厌脂性,所以不易通过血脑屏障,其中枢抑制作用因而不明显。它们因此被称为非镇 The main drawback of traditional antihistamines is that there are mostly side effects of central suppression. The second generation of antihistamines is mainly produced to overcome this side effect. However, they still have some side effects, some of which are still quite serious and should be given due attention. Central Inhibition Most second-generation antihistamines have paralytic, so they are not easy to cross the blood-brain barrier and their central inhibitory effects are not obvious. They are therefore called non-towns