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目的 观察胃镜下局部清创术治疗消化性溃疡 (Pu)的疗效和复发率。方法 10 0例十二指肠溃疡(Du)和 66例胃溃疡 (Gu)各分成治疗组和对照组 ,治疗组胃镜下清创术 (用毛刷刷掉Pu表面的坏死组织 ,再用活检钳咬除Pu周围的瘢痕组织 )后服枸橼酸铋钾、雷尼替丁、羟氨苄青霉素治疗 ,对照组只用药物治疗。结果 Du4周治愈率治疗组 98% ,对照组 82 %。Gu 6周治愈率治疗组 96% ,对照组 78%。Du 1、2年后复发率治疗组 9%和 15 % ,对照组 3 2 %和 47% ,Gu治疗组和对照组分别是 8%、12 %和 2 6%、3 8%。Pu的治愈率和复发率与对照组比较均有明显差异 (P <0 0 5 )。结论 清创疗法显著提高Pu治愈率和降低复发率
Objective To observe the curative effect and recurrence rate of partial debridement under endoscopy in the treatment of peptic ulcer (Pu). Methods One hundred and ten cases of duodenal ulcer (Du) and 66 cases of gastric ulcer (Gu) were divided into treatment group and control group. The patients underwent gastroscopic debridement (brushing off the surface of Pu tissue with a brush and then biopsy Clamp bite in addition to scar tissue around Pu) after taking bismuth potassium citrate, ranitidine, amoxicillin treatment, the control group only with drug treatment. Results The cure rate of Du4 weeks was 98% in the treatment group and 82% in the control group. Gu 6 weeks cure rate of 96% in the treatment group, 78% of the control group. Du 1, the recurrence rates after 2 years were 9% and 15% in the treatment group and 32% and 47% in the control group, respectively, and 8%, 12% and 26% and 38% in the Gu treatment group and the control group respectively. Pu cure rate and recurrence rate compared with the control group were significantly different (P <0 05). Conclusion Debridement therapy significantly increases the cure rate of Pu and reduces the recurrence rate