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目的比较Foley尿管水囊与前列腺素制剂促宫颈成熟用于晚期妊娠引产的有效性与安全性。方法计算机检索Cochrane Library、Embase、Pub Med、Elsevier全文电子期刊数据库、万方医学数据库、中国知网数据库、维普全文数据库,搜集关于Foley尿管水囊和前列腺素制剂用于晚期妊娠引产文献。采用Revman5.2版软件对数据进行Meta分析。结果共纳入文献30篇,Meta分析结果显示:Foley尿管水囊组与前列腺素制剂组比较,前者过强宫缩风险低于后者,差异有统计学意义[OR=0.38,95%CI(0.19,0.75),P<0.05],两组剖宫产率、阴道分娩率、宫颈Bishop评分的改善、引产至分娩时间、新生儿出生体质量、新生儿窒息率等方面均差异无统计学意义。结论 Foley尿管水囊用于晚期妊娠促宫颈成熟效果及母婴结局较好,极少发生过强宫缩,安全性较好;其有效性与前列腺素制剂相当,简单易行,值得临床推广。
Objective To compare the effectiveness and safety of Foley catheter balloon and prostaglandin preparations to promote cervical ripening for late pregnancy induction of labor. Methods The Cochrane Library, Embase, Pub Med, Elsevier Ejournal Database, Wanfang Medical Database, CNKI Database and Vip Database were searched by computer to collect literature about Foley catheter balloon and prostaglandin preparations for induction of late pregnancy. Meta-analysis of the data using Revman5.2 software. Results A total of 30 articles were included in the literature. Meta-analysis showed that the risk of over-contractions in the Foley group was significantly lower than that in the prostaglandin group (OR = 0.38, 95% CI ( 0.19, 0.75), P <0.05]. There was no significant difference in cesarean section rate, vaginal delivery rate, cervical Bishop score, induction labor to delivery time, birth weight, neonatal asphyxia . Conclusions Foley catheter balloon used in late pregnancy to promote cervical maturation and maternal and infant outcomes are better, rarely occur too strong contractions, safety is better; its effectiveness is equivalent to prostaglandin preparations, simple and feasible, worthy of clinical promotion .