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目的探讨肝病患者白细胞检测时假性增高原因及纠正措施。方法应用ABX60五分类全自动学细胞分析仪和雅培CD1200三分类血液分析仪以及手工方法对12例肝病患者进行对比分析,以保证白细胞计数的准确性。结果肝病高胆红素患者,红细胞膜抗溶性增强对ABX60血分析仪白细胞计数存在干扰。CD1200与手工方法结果一致,CD1200可得到正确结果。结论使用ABX60学细胞分析仪对肝病黄疸患者白细胞计数是有假性增高现象,应用CD1200可得准确结果。
Objective To investigate the cause of false increase of leucocyte in patients with liver disease and its corrective measures. Methods The ABX60 five class automatic cell analyzer and Abbott CD1200 three class blood analyzer and manual method were used to compare and analyze 12 cases of liver disease in order to ensure the accuracy of white blood cell count. Results In patients with hepatobiliary hyperbilirubinemia, the enhanced erythrocyte membrane anti-solubility could interfere with the white blood cell count of ABX60 analyzer. CD1200 is consistent with the manual method, CD1200 can get the correct result. Conclusions The use of the ABX60 cytometer has a false increase in leukocyte counts in patients with hepatocellular jaundice and accurate results are obtained using CD1200.