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目的分析影响脑梗死后认知功能障碍的因素、临床特征。方法将收治的脑梗死后认知功能障碍患者60例作为观察组,将脑梗死未发生认知功能障碍患者60例作为对照组,比较2组影响因素的差异,分析临床特征,评估预后。结果高龄、多发病灶、高血压、糖尿病、高脂血症、吸烟、饮酒均是导致脑梗死后认知功能障碍的主要因素。观察组记忆力、回忆力、计算与注意力、语言能力和MMSE均低于对照组(P<0.01);观察组住院时间长于对照组,入院时和出院时BI均低于对照组,出院时NIHSS评分高于对照组(P均<0.01)。结论脑梗死会导致认知功能障碍,易造成记忆力、注意力等减退,出现神经功能缺损致生活能力下降,影响预后。
Objective To analyze the influencing factors and clinical features of cognitive dysfunction after cerebral infarction. Methods 60 patients with cognitive dysfunction after cerebral infarction were treated as observation group, and 60 patients with cerebral infarction without cognitive impairment were used as control group. The differences of influencing factors between the two groups were compared. The clinical features were analyzed and the prognosis was evaluated. Results Older age, multiple lesions, hypertension, diabetes, hyperlipidemia, smoking, alcohol consumption were the main factors leading to cognitive dysfunction after cerebral infarction. The scores of memory, memory, calculation and attention, language ability and MMSE of the observation group were lower than those of the control group (P <0.01). The length of stay in the observation group was longer than that of the control group. The BI at admission and at discharge were lower than those in the control group. Score higher than the control group (P <0.01). Conclusions Cerebral infarction can lead to cognitive dysfunction, easily lead to memory loss, attention loss and so on. Decreasing of living ability caused by neurological deficit affects prognosis.