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近年来,胰腺癌发病率呈逐年上升趋势,早诊率低,手术切除率低,恶性程度高,预后极差,发病人数与死亡人数的比值接近1。目前放化疗联合姑息性手术的综合治疗是局部晚期及转移性胰腺癌的主要治疗手段,主要目的在于提高生活质量,延长生命。吉西他滨是目前的标准治疗,以其为主的联合方案的疗效亦有越来越多的循证医学证据支持。与靶向药物联合有一定的疗效。随着新的化疗药物和靶向药物的涌现,给晚期胰腺癌的治疗带来新的希望。
In recent years, the incidence of pancreatic cancer showed an upward trend year by year, with a low rate of early diagnosis, a low rate of surgical resection, a high degree of malignancy, and a very poor prognosis. The ratio of the number of cases to the number of deaths is close to one. Radiotherapy combined with palliative surgery is the treatment of locally advanced and metastatic pancreatic cancer, the main purpose is to improve the quality of life and prolong life. Gemcitabine is the current standard of care and the efficacy of its combined regimens is supported by evidence-based evidence. Combined with targeted drugs have a certain effect. With the advent of new chemotherapy drugs and targeted drugs, the treatment of advanced pancreatic cancer brings new hope.