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方法 30只成年猪全麻后开胸,肝素化,用套圈器阻断左冠状动脉第2、3对角支,共90分钟。然后插管建立体外循环,开始转流,主动脉阻断,心脏停跳45分钟。心脏停跳期间,动物分3组,采用3种灌注方法。①A/RGBC组10只,用4℃冷血停跳液灌注,5只顺灌,5只逆灌,首剂10ml/kg,然后每20分钟准一次5ml/kg,并局部降温,体温降
Methods Thirty adult pigs underwent thoracotomy and heparinization after general anesthesia. The second and third diagonal branches of the left coronary artery were blocked by a ferrule for 90 minutes. Then intubation to establish cardiopulmonary bypass, start bypass, aortic block, heart beating 45 minutes. During cardiac arrest, animals were divided into 3 groups, using 3 perfusion methods. ①A / RGBC group, 10 rats were perfused with cold blood cardioplegia at 4 ℃, 5 rats were fed with cisplatin, 5 rats were injected with the first dose of 10ml / kg, then 5ml / kg every 20 minutes,