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目的:探讨妊娠期高血压疾病患者白细胞参数及超敏C反应蛋白(CRP)的变化及临床意义。方法:采用sysmex-XE1800i血常规分析仪对200例正常晚期妊娠妇女及120例妊娠期高血压疾病患者进行白细胞参数检测,并采用散射比浊法测定其超敏CRP值,观察其变化及临床意义。结果:妊娠期高血压疾病组与正常晚期妊娠妇女组比较白细胞总数、中性粒细胞绝对值及超敏CRP值明显升高,差异有统计学意义(P<0.05)。结论:系统炎症反应在妊娠期高血压疾病的发生中具有重要作用,检测白细胞参数及超敏CRP的变化对评估和治疗监测妊娠期高血压疾病具有重要的临床意义。
Objective: To investigate the changes and clinical significance of leukocyte parameters and high sensitive C reactive protein (CRP) in patients with hypertensive disorders during pregnancy. Methods: The leukocyte parameters were detected in 200 normal pregnant women and 120 pregnant women with hypertensive disorders by using sysmex-XE1800i hematology analyzer. The CRP values were measured by nephelometry. The changes and clinical significance were observed . Results: The total number of leukocytes, absolute neutrophil and high CRP were significantly higher in gestational hypertension patients than in normal pregnant women (P <0.05). Conclusions: The systemic inflammatory response plays an important role in the development of hypertensive disorders in pregnancy. The detection of leukocyte parameters and the changes of hypersensitive CRP are of great clinical significance for the assessment and treatment of hypertensive disorders in pregnancy.