心房颤动(AF)是临床常见的心律失常,在人群中的患病率正在不断增高,严重影响患者的生活质量。虽然近年来不乏对AF的基础和临床研究,也取得了一些进步,但其发病机制尚不明确。炎症作为近几年对AF较有影响的因素备受关注。现就影响AF的炎性因子及可能发病机制作一综述,以AF的病理生理学为基础,在对C反应蛋白、白细胞介素6、白细胞介素18等炎性因子的研究中阐述炎症在AF中可能的作用机制。 Atrial fibrillation (AF) is a common clinical arrhythmia, the prevalence in the population is rising, seriously affecting the quality of life of patients. Although there is no lack of basic and clinical research on AF in recent years, some progress has been made, but its pathogenesis is still not clear. Inflammation has drawn much attention as a contributing factor to AF in recent years. Now on the impact of AF inflammatory cytokines and possible pathogenesis made a review of the pathophysiology of AF based on the C-reactive protein, interleukin 6, interleukin 18 and other inflammatory factors in the study described inflammation in the AF In the possible mechanism of action.