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目的分析脑卒中后癫痫发作的临床特点,并对其相关因素进行分析。方法对1 008例脑卒中患者进行回顾性研究,并分析可能影响卒中后继发癫痫发作的相关危险因素。结果脑卒中后癫痫发作的发生率约为5.36%,其中早发型癫痫占63.11%,发作类型以单纯部分发作为主,迟发型癫痫占38.89%,发作类型以全身强直-阵挛发作为主,单因素分析结果显示:性别(x~2=4.12,P=0.042)、糖尿病(x~2=4.89,P=0.027)、肺部感染(x~2=8.95,P=0.003)、病灶部位(x~2=45.14,P<0.001)和病灶范围(x~2=23.32,P<0.001)与卒中后癫痫发作有关;多元Logistic分析结果显示:性别(OR=1.946,95%CI:1.039~3.644)、肺部感染(OR=3.618,95%CI:1.536~8.520)、病灶部位(OR=6.435,95%CI:3.353~12.349)和病灶范围(OR=2.513,95%CI:1.374~4.599)等因素可能与卒中后癫痫发作有关(均有P<0.05)。结论男性,肺部有感染,病灶部位在皮质和病灶范围大可能是卒中后癫痫发作的危险因素。
Objective To analyze the clinical features of seizures after stroke and analyze its related factors. Methods One hundred and eighty stroke patients were retrospectively analyzed, and the related risk factors that may affect secondary seizures after stroke were analyzed. Results The incidence of seizure after stroke was about 5.36%, of which 63.11% were early-onset epilepsy. The type of seizures was mainly partial seizures, delayed seizures accounted for 38.89%, seizure type was mainly tonic-clonic seizures, The results of univariate analysis showed that there was no significant difference between the two groups (x 2 = 4.12, P = 0.042), diabetes (x 2 = 4.89, P = 0.027) (P = 0.001), and range of lesions (x ~ 2 = 23.32, P <0.001) were associated with post-stroke seizure. Multivariate Logistic analysis showed that gender (OR = 1.946, 95% CI: 1.039-3.654 ), Pulmonary infection (OR = 3.618, 95% CI: 1.536-8.520), lesion location (OR = 6.435,95% CI: 3.353-12.349) And other factors may be related to post-stroke seizures (both P <0.05). Conclusions Male and pulmonary infection, and the location of the lesion in the cortex and lesion may be the risk factors of post-stroke seizure.