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目的了解海口地区小儿TWAR感染情况及探讨其临床特点。方法应用聚会酶链反应（PCR）技术，对931例病史较长或普通抗菌素治疗效果差的呼吸道感染病人。结果阳性101例．总阳性率10．85％，其中住院病人78例，年龄最小23天，最大11岁；发病时间平均13．5天；诊断以肺炎居多，3例合并浆腹腔积液。所有病例均有咳嗽，体温以低热为主，52．56%的病人有喘鸣音；治疗以阿奇霉素最佳。结论TWAR是儿童呼吸道感染的重要病原体，应引起我省儿科医师的重视。
Objective To understand the situation of pediatric TWAR infection in Haikou and to explore its clinical features. Methods Polymerase chain reaction (PCR) was used in 931 patients with respiratory tract infection who had a longer history or poor general antibiotic treatment. 101 cases were positive. The total positive rate of 10.85%, of which 78 cases were hospitalized, the youngest 23 days, maximum 11 years old; onset time averaged 13.5 days; diagnosis of mostly pneumonia, 3 cases of combined ascites fluid. All cases had cough, body temperature with low fever, 52.56% of patients have wheezing; treatment with azithromycin best. Conclusion TWAR is an important pathogen of respiratory tract infection in children and should be paid attention to by pediatricians in our province.