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目的:观察足月新生儿黄疸(高胆红素血症)采取茵栀黄口服液治疗的临床效果。方法:将北京市西城区(原宣武区)妇幼保健院产科及儿科2007年5月—2011年1月接诊的足月新生儿高胆红素血症86例作为研究对象,回顾性分析他们的临床资料,随机均分为研究组与对照组,各自43例,其中对照组采取蓝光照射治疗,而研究组在对照组基础上加用茵栀黄口服液治疗,观察记录两组患儿临床疗效与不良反应及治疗前后胆红素水平变化情况,并对比分析。结果:研究组治疗总有效率为95.34%,对照组则为83.72%,研究组明显优于对照组(P<0.05);研究组不良反应发生率为6.98%,对照组则为18.60%,研究组明显低于对照组(P<0.05);两组治疗后胆红素皆有一定下降,但研究组下降更明显,组间对比差异有统计学意义(P<0.05)。结论:足月新生儿黄疸属于儿科常见疾病,在常规蓝光照射基础上予以茵栀黄口服液治疗可以取得良好的效果,总有效率高,不良反应少,同时能明显改善胆红素水平,值得借鉴。
Objective: To observe the clinical effect of taking Yinzhihuang Oral Liquid in full-term neonatal jaundice (hyperbilirubinemia). Methods: 86 cases of full-term newborns with hyperbilirubinaemia admitted from May 2007 to January 2011 in Xicheng District (formerly Xuanwu District) Maternal and Child Health Hospital of Beijing City were retrospectively analyzed Of the clinical data were randomly divided into study group and control group, 43 cases each, in which the control group to take blue light irradiation, while the study group in the control group based on the use of Yinzhihuang oral liquid treatment, the observation records of two groups of children clinical Efficacy and adverse reactions and changes in bilirubin levels before and after treatment, and comparative analysis. Results: The total effective rate was 95.34% in the study group and 83.72% in the control group, which was significantly better in the study group than in the control group (P <0.05). The incidence of adverse reactions in the study group was 6.98% and that in the control group was 18.60% (P <0.05). The bilirubin levels in both groups decreased after treatment, but the decrease in the study group was more obvious. The difference between the two groups was statistically significant (P <0.05). Conclusion: Full-term neonatal jaundice belongs to the common pediatric diseases. Yinzhihuang oral liquid can be treated with routine blue light irradiation with good effect, high total effective rate, few adverse reactions and significant improvement of bilirubin level. Learn from