贝前列素钠(beraprost sodium,1),化学名为2,3,3a,8b-四氢-2-羟基-1-(3-羟基-4-甲基-1-辛烯-6-炔基)-1H-环戊并[b]苯并呋喃-5-丁酸钠,是日本Toray Industries公司开发的抗血小板药物,商品名为Dorner。贝前列素是第一个生物学稳定、具有口服活性的前列环素类似物[1]。1992年贝前 Beraprost sodium (1), with the chemical name 2,3,3a, 8b-tetrahydro-2-hydroxy-l- (3- hydroxy-4-methyl-l-octen-6-ynyl ) -1H-cyclopenta [b] benzofuran-5-butyrate, an anti-platelet drug developed by Toray Industries, Japan, under the trade name Dorner. Beraprost is the first biologically stable, orally active prostacyclin analogue [1]. In 1992 before the shellfish