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Toll样受体(TLR)是先天免疫模式识别受体中最重要的受体家族之一。在人类许多组织和细胞中都有表达,并有重要的生理功能。本综述重点介绍近年来TLR在肠道尤其是肠黏膜屏障中免疫作用机制的研究进展。
Toll-like receptors (TLRs) are one of the most important receptor families in innate immune pattern recognition receptors. It is expressed in many tissues and cells of humans and has important physiological functions. This review focuses on the recent progress in the study of the immunological mechanism of TLR in the gut, especially the intestinal mucosal barrier.