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目的:评价头孢呋辛对原发性肝癌患者介入术后感染发生率的影响。方法:选取2011年2月—2014年2月间实施介入手术治疗的原发性肝癌患者200例,依照患者的头孢呋辛应用情况将其分为对照组和观察组,每组100例;其中对照组患者均不给予头孢呋辛治疗,观察组患者均给予头孢呋辛治疗,比较两组患者治疗后的相关情况的变化。结果:观察组患者的术后发热发生率显著低于对照组(P<0.05);两组患者的白细胞升高和发热并白细胞计数升高的发生率、血培养阳性率及术后感染的发生率经比较其差异无统计学意义(P>0.05)。结论:原发性肝癌患者介入术后使用头孢呋辛预防感染,对感染的影响不大。
Objective: To evaluate the effect of cefuroxime on the incidence of postoperative infection in patients with primary liver cancer. Methods: A total of 200 patients with primary hepatocellular carcinoma who underwent interventional procedures between February 2011 and February 2014 were enrolled in this study. Patients were divided into two groups according to the application of cefuroxime: control group and observation group, 100 cases in each group Patients in the control group were not treated with cefuroxime, patients in the observation group were treated with cefuroxime, and the changes of the two groups after treatment were compared. Results: The incidence of postoperative fever in the observation group was significantly lower than that in the control group (P <0.05). The incidence of leukocytosis and fever and leukocyte count increase, the positive rate of blood culture and postoperative infection Rate after the difference was not statistically significant (P> 0.05). Conclusion: The use of cefuroxime for the prevention of infection in patients with primary liver cancer after the intervention has little effect on the infection.