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1961年1月至1965年12月5年间,我科采用合霉素治疗407例内科住院病例中,发生各种副作用者71例。服药剂量成人2-4克/日,小儿每日每公斤体重50-100毫克,均口服。连续服药时间短者2天,长者22天。本文发生副作用之71例,小儿7/114例,成人64/293例,副作用的发生似与年龄有一定关东。其中药物疹42例,占服药总人数10.3％;精神症状13例(3.2％);腹泻8例(2％);呕吐5例(1.2％);药物热2例(0.5％);视力模糊1例(0.24％)。副作用发生时间均在服药2-11日之间,平均药物热5.5天,呕吐5天,药物疹4.95
From January 1961 to December 1965, 5 years, our department adopted actomycin to treat 407 cases of medical inpatients with various side effects in 71 cases. Dosage 2-4g adults / day, children per kilogram of body weight 50-100 mg per day, are oral. Continuous medication for a short period of 2 days, the elderly 22 days. 71 cases of side effects occurred in this article, 7/114 children, 64/293 adults, the occurrence of side effects and age of some Kanto. Among them, 42 cases of drug rash accounted for 10.3% of the total number of patients taking medication; 13 cases (3.2%) of psychiatric symptoms, 8 cases of diarrhea (2%), 5 cases of vomiting (1.2%), 2 cases of drug fever Example (0.24%). Side effects occurred in the medication 2-11 days, the average drug fever 5.5 days, vomiting for 5 days, the drug rash 4.95