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目的分析对乙酰氨基酚致儿童不良反应的发生特征及规律。方法对2015年9月-2016年9月在我院救治的90例上呼吸道感染伴高热患儿进行分析。先将所有患儿按照抽签法分为对照组和分析组,每组45例,其中对照组采用布洛芬进行治疗,分析组采用对乙酰氨基酚进行治疗;比较两组患儿的临床疗效和不良反应。结果分析组的有效例数为37例,有效率为82.22%;对照组的有效例数为23例,有效率为51.11%;组间差异较大,有统计学意义(P<0.05)。分析组的不良反应总发生率为4.44%,对照组的不良反应总发生率为17.78%;对照组的不良反应发生率明显高于分析组,组间差异较大,有统计学意义(P<0.05)。结论将对乙酰氨基酚用于治疗上呼吸道感染伴高热患儿疗效较好,不良反应发生率较低,可进行临床大量推广。
Objective To analyze the characteristics and regularities of adverse reactions caused by acetaminophen in children. Methods 90 cases of upper respiratory tract infection with fever in our hospital from September 2015 to September 2016 were analyzed. First, all children were divided into control group and analysis group according to the drawing method, with 45 cases in each group. The control group was treated with ibuprofen, and the analysis group was treated with acetaminophen. The clinical efficacy and Adverse reactions. Results The number of effective cases in the analysis group was 37 cases, the effective rate was 82.22%. The effective number of cases in the control group was 23 cases, the effective rate was 51.11%. The difference between the two groups was statistically significant (P <0.05). The total incidence of adverse reactions in the analysis group was 4.44%, while the incidence of adverse reactions in the control group was 17.78%. The incidence of adverse reactions in the control group was significantly higher than that in the analysis group, with significant difference between the two groups (P < 0.05). Conclusion Acetaminophen for the treatment of upper respiratory tract infection with high fever in children with better efficacy, the incidence of adverse reactions is low, a lot of clinical promotion.