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目的:探讨长托宁联合氯磷定治疗急性有机磷农药中毒的临床疗效。方法:选取急性有机磷农药中毒患者88例,随机分为研究组和对照组,每组患者44例,研究组长托宁与氯磷定联合治疗,对照组阿托品与氯磷定联合治疗,并分别对两组患者的临床症状改善情况和临床治疗效果进行比较和分析。结果:研究组与对照组相比,临床症状消失时间、胆碱酯酶活力恢复时间、住院时间均明显缩短,治愈率显著提高,反跳和死亡率则显著降低,差别均具统计学意义(P<0.05)。结论:长托宁联合氯磷定对于抢救急性有机磷农药中毒具有极其显著的临床治疗效果,能够为进一步提高急性有机磷农药中毒的临床救治水平发挥积极的推动作用。
Objective: To investigate the clinical effect of pendimethalin combined with chlorophosphon in the treatment of acute organophosphorus pesticide poisoning. Methods: A total of 88 patients with acute organophosphorus pesticide poisoning were selected and randomly divided into study group and control group, with 44 patients in each group. The study group leader was combined with chlorophosphorus, and the control group was treated with combination of chlorophosphorus and atropine The improvement of clinical symptoms and the clinical effect of the two groups were compared and analyzed respectively. Results: Compared with the control group, the disappearance time of clinical symptoms, recovery time of cholinesterase activity and length of stay in study group were significantly shortened, the cure rate was significantly increased, rebound and mortality were significantly decreased, the differences were statistically significant ( P <0.05). Conclusion: The combination of pendimethalin and chlorpromazine has an extremely significant clinical effect in salvage acute organophosphorus pesticide poisoning, which can play an active role in further improving the clinical treatment of acute organophosphorus pesticide poisoning.