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目的观察子宫动脉化疗栓塞术治疗Ⅱb~Ⅳa期宫颈癌患者的临床疗效并评价子宫动脉化疗栓塞术在宫颈癌治疗中的远期疗效。方法 2014年6月—2016年12月黄河水利委员会黄河中心医院收治的纳入符合条件的中晚期宫颈癌患者60例,随机分为两组,30例患者采用介入子宫动脉灌注化疗栓塞术(化疗栓塞组),30例患者同期行宫颈癌放射治疗(放疗组),对比两组患者治疗前后的肿瘤变化情况、症状缓解情况、根治手术情况及远期疗效等。结果子宫动脉化疗栓塞组与放疗组比较肿瘤变化情况、临床症状改善情况、骨髓抑制情况、淋巴结转移情况的差异有统计学意义(P<0.05)。结论介入子宫动脉化疗栓塞术是中晚期宫颈癌的安全、有效的治疗方法,较放疗可有效改善相关术后并发症。
Objective To observe the clinical efficacy of uterine arterial chemoembolization in patients with stage Ⅱb-Ⅳa cervical cancer and to evaluate the long-term efficacy of uterine artery chemoembolization in the treatment of cervical cancer. Methods June 2014 to December 2016 Sixty consecutive patients with advanced cervical cancer who were admitted to the Yellow River Central Hospital of the Yellow River Conservancy Commission were randomly divided into two groups. Thirty patients were treated by interventional uterine arterial chemoembolization (chemoembolization Group), 30 patients underwent radiotherapy (radiotherapy group) for cervical cancer at the same period. The changes of tumor, symptom relief, radical operation and long-term efficacy of the two groups before and after treatment were compared. Results There were significant differences in tumor changes, clinical symptoms, bone marrow suppression and lymph node metastasis between uterine artery chemoembolization group and radiotherapy group (P <0.05). Conclusion Interventional chemotherapy for uterine artery embolization is a safe and effective treatment for advanced cervical cancer. Compared with radiotherapy, the postoperative complications can be effectively improved.