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目的观察辛伐他汀治疗冠心病并高脂血症的临床治疗效果。方法选取90例冠心病并原发性高脂血症患者,每晚服用辛伐他汀20mg,疗程6周,观察血脂变化。结果治疗6周后总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)较治疗前显著下降(P<0.01),高密度脂蛋白胆固醇(HDL-C)也明显升高(P<0.05)。结论辛伐他汀降脂疗效确切,不良反应少,安全可靠。
Objective To observe the clinical effect of simvastatin on patients with coronary heart disease and hyperlipidemia. Methods 90 patients with coronary heart disease and primary hyperlipidemia were treated with simvastatin 20 mg every night for 6 weeks. The changes of blood lipids were observed. Results After 6 weeks of treatment, the levels of total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) were significantly lower than those before treatment (P <0.01). High density lipoprotein cholesterol Was significantly higher (P <0.05). Conclusions Simvastatin has definite effects on lipid-lowering, less adverse reactions, and is safe and reliable.