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免疫制品狂犬病的免疫制品有两种:(1)诱发主动免疫反应的疫茁,约需7～10天出现免疫作用,但可持续1年以上;(2)提供快速被动免疫保护的球蛋白,持续时间短,半衰期约21天。狂犬病暴露后的预防,应同时使用这两种制品。一、疫苗:美国应用的是人双倍体细胞狂犬病疫苗(HDCY),系灭活病毒疫苗。由WI-38或 MRC-5人双倍体细胞培养中生长的狂犬病毒经固定而成。在美国制成的 WI-38细胞培养中生长的狂犬病毒疫苗,用3-氮-丁基磷酸盐和β-丙内脂灭活,而在欧洲
Immunization Rabies products are two kinds of immune products: (1) the immune response induced immune crisis, about 7 to 10 days of immunization, but sustainable for more than 1 year; (2) to provide rapid passive immunoglobulin protection, Short duration, half-life of about 21 days. Rabies exposure after the prevention, should use both products. First, the vaccine: the United States is the application of human diploid cell rabies vaccine (HDCY), Department of inactivated virus vaccine. Rabies virus was grown from either WI-38 or MRC-5 human diploid cell cultures. Rabies virus vaccine grown in the USA in WI-38 cell culture was inactivated with 3-azido butyl phosphate and beta-propiolactone, whereas in Europe