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目的通过分析克拉玛依市2013年-2015年流感病毒病原学检测结果,了解流感病毒病原学特征,为当地流感的防控提供科学的理论依据。方法采用实时荧光定量PCR的方法进行流感样病例咽拭子的检测。结果 2013年-2015年共采集流感样病例咽拭子2 097份,阳性样本427份,总阳性率为20.36%,其中H3型阳性率最高,为9.20%。3年不同型别的检测阳性率差异有统计学意义(χ2=280.77,P<0.05)。克拉玛依市流感流行的高峰季节在冬春季,不同年龄组的阳性率差异无统计学意义(χ2=6.760,P>0.05)。2013年-2015年各年龄段间不同型别的流感病毒阳性率差异无统计学意义(χ2=7.133,P>0.05)。结论克拉玛依地区流感监测工作应重点关注季节性H3型,流感病原学流行情况随着时间变化,应加强监测,密切关注变化情况,及时采取措施。
Objective To understand the etiological characteristics of influenza virus by analyzing the results of influenza virus etiology from 2013 to 2015 in Karamay City and to provide a scientific theoretical basis for prevention and control of local influenza. Methods The real-time fluorescence quantitative PCR method was used to detect throat swabs in influenza-like cases. Results A total of 2 097 throat swabs were collected from 2013 to 2015, including 427 positive samples, the total positive rate was 20.36%. The highest positive rate of H3 was 9.20%. The difference of positive rate of different types of 3 years was statistically significant (χ2 = 280.77, P <0.05). There was no significant difference in the positive rates among different age groups in Karamay during winter and spring (χ2 = 6.760, P> 0.05). There was no significant difference in the positive rates of different types of influenza viruses between 2013 and 2015 (χ2 = 7.133, P> 0.05). Conclusion Influenza surveillance in Karamay should focus on seasonal H3. Flu prevalence changes over time, monitoring should be strengthened, pay close attention to changes, and take timely measures.