论文部分内容阅读
本文评价钙通道阻滞剂治疗肾病合并高血压患者的疗效,并研究其对肾功、肾和全身血液动力学及水-电解质平衡的影响。 46例慢性肾小球肾炎合并高血压的患者,20例应用硝苯啶,每天40～120mg;14例应用心可定,每天80～140mg;12例应用异搏定,每天240～400mg。所有患者均有中度蛋白尿(2.2±0.3 g/L),尿沉渣无明显异常,形态学确诊者18例。初始动脉压平均值:收缩压21.75±0.37 kPa,舒张压14.44±0.15 kPa。肾功代偿期20例,肾功降低者26例(血肌酐浓度133～310μmo1/L)。
This article evaluates the efficacy of calcium channel blockers in the treatment of patients with nephropathy and hypertension and studies their effects on kidney function, kidney and systemic hemodynamics and water-electrolyte balance. 46 cases of chronic glomerulonephritis with hypertension in patients with nifedipine 20 cases, 40 ~ 120mg daily; 14 cases of application of the heart can be set, daily 80 ~ 140mg; 12 cases of verapamil daily 240 ~ 400mg. All patients had moderate proteinuria (2.2 ± 0.3 g / L), no obvious urinary sediment abnormalities, 18 cases of morphologically diagnosed. Initial mean arterial pressure: systolic blood pressure 21.75 ± 0.37 kPa, diastolic blood pressure 14.44 ± 0.15 kPa. 20 cases of compensatory renal function, 26 cases of decreased renal function (serum creatinine concentration 133 ~ 310μmo1 / L).