论文部分内容阅读
目的观察小剂量催产素联合间苯三酚在终止孕41~41+6周妊娠中的效果。方法住院分娩孕41~41+6孕妇126例随机分为观察组与对照组各63例,对照组静脉滴注催产素,观察组催产素用法及剂量同对照组,并静脉注射间苯三酚,比较2组用药后6、12、24h宫颈Bishop评分,用药24h内临产率,产后出血量,新生儿Apgar评分,羊水污染情况。结果观察组用药后6、12、24h宫颈Bishop评分分别为(7.0±0.3)、(7.2±0.4)和(7.5±0.8)分,对照组分别为(6.0±0.1)、(6.2±0.2)、(6.8±0.5)分,2组各时间点比较差异有统计学意义(P<0.01);观察组用药24h内临产率(82.53%)高于对照组(53.97%)(P<0.01);观察组产后出血量(150±20)mL、新生儿Apgar评分(9.89±0.11)分、羊水污染8例,对照组产后出血量(155±20)mL、新生儿Apgar评分(9.88±0.12)分、羊水污染9例,2组比较差异无统计学意义(P>0.05)。结论小剂量催产素联合间苯三酚可促进宫颈成熟,缩短产程,用于终止孕41~41+6周妊娠效果优于单纯小剂量催产素引产。
Objective To observe the effect of low dose oxytocin combined with phloroglucinol in the termination of pregnancy 41 ~ 41 + 6 weeks of pregnancy. Methods A total of 126 pregnant women with 41 to 41 + 6 pregnant women were randomly divided into observation group (63 cases) and control group (63 cases). Oxytocin was intravenously instilled into the control group. Oxytocin administration and dosage were observed in the control group, and phloroglucinol The Bishop cervical score at 6, 12 and 24 hours after treatment was compared between the two groups. The intrapartum labor rate, postpartum hemorrhage, neonatal Apgar score and amniotic fluid contamination were compared. Results The Bishop scores of the cervix in the observation group were (7.0 ± 0.3), (7.2 ± 0.4) and (7.5 ± 0.8) at 6, 12 and 24 hours after treatment, respectively, and were 6.0 ± 0.1 and 6.2 ± 0.2 in the control group (6.8 ± 0.5). There was significant difference between the two groups at each time point (P <0.01). The observation group was significantly higher than the control group (82.53%, P <0.01) The postpartum hemorrhage (150 ± 20) mL, Apgar score (9.89 ± 0.11), amniotic fluid contamination in the neonates, postpartum hemorrhage volume (155 ± 20) mL and Apgar score (9.88 ± 0.12) Amniotic fluid contamination in 9 cases, two groups showed no significant difference (P> 0.05). Conclusion Low-dose oxytocin combined with phloroglucinol can promote cervical maturation and shorten the labor process. It is superior to the simple low-dose oxytocin induction in terminating the pregnancy of 41-41 + 6 weeks.