论文部分内容阅读
以S180肉瘤细胞移植于昆明小鼠前肢右腋窝皮下,随机分为阴性对照组(水组)、镓组、镓锗组及镓硒组。每日胃饲一次,2周后,取出肿瘤称重并设正常对照组,并摘取前肢骨骼,测骨中镓、磷、钙含量。结果提示胃饲给药组、三组瘤重显著低于水组,抑制率分别为64.6%、52.6%及54.9%。骨中镓含量,给药组皆大于正常组及水组,口服镓盐皆能进入骨质。镓锗组骨镓含量低于镓组。可能锗拮抗了镓进入骨,而镓硒组骨镓含量则高于镓组,显示硒有促进镓进入骨的作用,镓硒联合应用可能有增强骨的作用。药物对骨中钙、磷含量未见影响。
S180 sarcoma cells were transplanted subcutaneously in the right armpit of the forelimb of Kunming mice and randomly divided into a negative control group (water group), a sacral group, a sacral group, and a selenium-selenium group. The stomach was fed once a day. After 2 weeks, the tumors were weighed out and set in a normal control group. Forelimb bones were removed and the contents of sputum, phosphorus and calcium in bones were measured. The results suggest that the weight of the tumors in the gastric feeding group and the three groups was significantly lower than that in the water group, and the inhibition rates were 64.6%, 52.6%, and 54.9%, respectively. The content of bone glycosides in the treatment group was greater than that in the normal group and the water group, and oral administration of barium salt could enter the bone. The content of callus in the quail group was lower than that in the iliac group It was possible that fleas could antagonize the inguinal invasion, whereas in the selenium-enriched selenium group, the content of osteophyte was higher than that of the indole group, indicating that selenium has the effect of promoting the invading of the alfalfa into bone. The drug had no effect on bone calcium and phosphorus content.