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[目的]研究高尿酸血症与脂肪肝的危险因素及二者的相关性。[方法]运用流行病学调查方法调查987例脂肪肝患者的一般资料、尿酸等生化指标。[结果]①987例脂肪肝患者高尿酸血症392例,男女尿酸水平比较差异有统计学意义(t′=16.00,P﹤0.01),男性组41～50岁达峰值(31.19%);女性组51～60岁达峰值(21.68%);χ2检验差别具有统计学意义(χ2=90.14,χ2=129.31,P﹤0.01)。②多因素Logistic回归分析,饮酒、超重、高甘油三酯患者高尿酸血症相对危险度明显增高;饮酒、肥胖、高甘油三酯、高尿酸患者脂肪肝相对危险度明显增高。[结论]高尿酸血症及脂肪肝患者中青年多见,高尿酸血症与饮酒、超重、高甘油三酯呈正相关,脂肪肝与高尿酸血症、肥胖、高甘油三酯密切正相关。
[Objective] To study the risk factors of hyperuricemia and fatty liver and their correlation. [Method] The epidemiological survey method was used to investigate the general data of 987 patients with fatty liver and the biochemical indexes of uric acid. [Results] ① There were 392 cases of hyperuricemia in 987 patients with fatty liver, the difference of uric acid level between male and female was statistically significant (t ’= 16.00, P <0.01), the peak was 41- 50 (31.19% The peak value of 51-60 years old (21.68%); χ2 test difference was statistically significant (χ2 = 90.14, χ2 = 129.31, P <0.01). (2) Multivariate Logistic regression analysis showed that the relative risk of hyperuricemia was significantly increased in alcohol, overweight and hypertriglyceridemia patients, and the relative risk of fatty liver was significantly higher in drinking, obesity, hypertriglyceridemia and hyperuricemia. [Conclusion] Hyperuricemia and fatty liver are more common in young patients. Hyperuricemia is positively correlated with drinking, overweight and high triglycerides. Fatty liver is closely related to hyperuricemia, obesity and high triglyceride.