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目的 :分析老年急性白血病临床特点 ,评价疗效。方法 :对初治的老年急性白血病 2 1例进行临床分析 ,其中 60岁～ 69岁 15例 ,70岁以上 6例 ,男性 14例 ,女性 7例 ,急性髓细胞白血病(AML) 16例 ,急性淋巴细胞白血病 (AL L) 5例。治疗以小到中剂量 HA、DA、EA、COMP及 HOAP等联合化疗或小剂量三尖杉酯碱、小剂量阿糖胞苷单药化疗。结果 :总 CR率 47.6% ,AML 组 CR率5 0 .0 % ,ALL组 CR率 40 .0 % ,60岁～ 69岁 CR率 5 3 .3 % ,70岁以上 3 3 .3 %。结论 :老年急性白血病临床上有其特殊性 ,治疗上更强调个体化。总的对化疗反应差 ,缓解率低 ,生存期短 ,死亡率高
Objective: To analyze the clinical features of senile acute leukemia and evaluate its curative effect. Methods: Clinical data of 21 newly diagnosed acute leukemia patients were analyzed. There were 15 cases aged 60 to 69 years, 6 cases aged 70 years and older, 14 males and 7 females, 16 cases of acute myeloid leukemia (AML), acute Lymphocytic leukemia (AL L) in 5 cases. Treatment with small to medium doses of HA, DA, EA, COMP and HOAP and other combination chemotherapy or small dose of harringtonine, low dose of cytarabine monotherapy. Results: The total CR rate was 47.6%. The CR rate was 50.0% in AML group, 40.0% in ALL group, 53.3% in 60-69 years old and 33.3% in 70 years old. Conclusion: The clinical features of acute leukemia in the elderly have their own particularities, the treatment is more emphasis on individualism. The overall response to chemotherapy, poor response rate, short survival, high mortality