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目的了解医疗体制改革前后脑梗死患者的药物治疗变化情况,探讨其用药合理性。方法分别调查1999年至2001年和2003年至2006年初次发生脑梗死患者的病历资料,统计、分析和对比用药情况。结果应用频度较高的药物包括脱水剂、利尿剂、抗血小板聚集药、改善脑血循环药、保护脑细胞药及支持治疗药。治疗合并症和并发症应用频率较高的药物依次为降压药、抗感染药、心脏病用药、降糖药及降脂药。保护脑细胞药物应用变化较大,抗感染药使用趋于合理。结论脑梗死住院患者用药种类繁多,故临床对药物的选择及合理应用应作深入研究。
Objective To understand the changes of drug treatment in patients with cerebral infarction before and after the medical system reform and to explore its rationality. Methods The records of the patients with cerebral infarction who had the first cerebral infarction from 1999 to 2001 and from 2003 to 2006 were surveyed, and the statistic, analysis and comparison were made. Results The more frequently used drugs include dehydrating agents, diuretics, anti-platelet aggregation drugs, cerebral blood circulation improving drugs, brain cytoprotection drugs and supportive therapies. Treatment of complications and complications of the higher frequency of drugs followed by antihypertensive drugs, anti-infectives, heart disease medication, hypoglycemic agents and lipid-lowering drugs. Changes in the application of drugs to protect brain cells, anti-infectives tend to be more rational use. Conclusion Inpatient cerebral infarction with a wide range of medication, so the clinical choice of drugs and rational application should be studied in depth.