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目的:评价青黄口含片与氨来呫诺糊剂联用治疗重型复发性口腔溃疡(重型RAU)患者的临床疗效。方法:选取医院2012年1月—2015年1月间收治的重型RAU患者50例,将其分为对照组(n=25例)与观察组(n=25例);对照组患者给予氨来呫诺糊剂治疗,观察组患者在对照组治疗基础上再给予青黄口含片治疗,比较两组患者治疗后的溃疡愈合情况。结果:经治疗观察组患者总有效率为92.00%高于对照组为76.00%(P<0.05);观察组患者溃疡愈合率为48.00%高于对照组为24.00%(P<0.05)。结论:青黄口含片与氨来呫诺糊剂联用治疗重型RAU患者临床疗效优于单用氨来呫诺糊剂治疗。
Objective: To evaluate the clinical efficacy of Qinghuangkou buccal tablets combined with amlexanox in the treatment of patients with severe recurrent oral ulcer (severe RAU). Methods: Fifty patients with severe RAU admitted from January 2012 to January 2015 in our hospital were divided into control group (n = 25) and observation group (n = 25). Patients in the control group were given ammonia Xanan paste treatment, the observation group patients in the control group based on the treatment given Qinghuangkou tablets treatment, the two groups were compared after treatment of ulcer healing. Results: The total effective rate was 92.00% in the treated group and 76.00% in the control group (P <0.05). The ulcer healing rate in the observation group was 48.00%, which was significantly higher than that in the control group (24.00%, P <0.05). Conclusion: The clinical curative effect of Qinghuangkou lozenges combined with amilasexide paste on patients with severe RAU is better than that of amilasexide alone.