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本文报道48例经CT和MRI证实的LA,3年随访发现40例CT和MRI损害程度进展1~2级,平均1.34级,进展率83.33%,8例无明显进展(16.67%);进展1级者CCSE得分平均降低3.4分,进展2级者CCSE得分平均降低7.2分。CT、MRI损害进展程度与智能衰退呈正向关。有效的控制高血压及高血糖可能能够防止或延缓LA的进展。
In this paper, 48 cases of LA confirmed by CT and MRI were followed up for 3 years. Forty CT and MRI lesions of grade 1 to 2 were diagnosed as grade 1 ~ 2 with an average of 1.34 grade and a rate of 83.33%. There was no significant progress in 8 cases (16. 67%). The CCSE score of Grade 1 was reduced by an average of 3.4 points and the Grade 2 of CCSE score was lowered by an average of 7.2 points. The progress of CT and MRI was positively correlated with the decline of intelligence. Effective control of hypertension and hyperglycemia may prevent or delay the progression of LA.