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目的观察无创正压通气治疗AECOPD所并发的Ⅱ型呼吸衰竭患者的临床疗效。方法回顾性分析2012年5月-2013年5月收住的62例AECOPD合并Ⅱ型呼吸功能衰竭患者,随机分为观察组和对照组各31例,对照组经鼻导管常规吸氧+药物治疗;治疗组即在对照组治疗基础上加用无创正压通气治疗,比较2组治疗前后临床疗效及实验室指标的变化。结果观察组患者的临床治疗效果,以及p H、Pa CO2、Pa O2、RR、HR的变化情况均明显好于对照组,2组比较差异有统计学意义(P<0.05)。结论无创正压通气治疗可明显改善AECOPD的临床症状和通气功能,对纠正Ⅱ型呼吸衰竭起到的良好作用,可有效控制疾病发展,疗效肯定。
Objective To observe the clinical efficacy of noninvasive positive pressure ventilation in the treatment of type Ⅱ respiratory failure complicated by AECOPD. Methods A retrospective analysis of 62 AECOPD patients with type Ⅱ respiratory failure admitted from May 2012 to May 2013 were randomly divided into observation group and control group, with 31 cases in each group. The control group received conventional oxygen inhalation and drug therapy The treatment group was treated with noninvasive positive pressure ventilation on the basis of the control group, and the clinical curative effect and laboratory indexes before and after treatment were compared. Results The clinical efficacy of the observation group and the changes of p H, PaCO 2, Pa O 2, RR and HR were significantly better than those of the control group. There was significant difference between the two groups (P <0.05). Conclusion Noninvasive positive pressure ventilation can significantly improve the clinical symptoms and ventilatory function of AECOPD, which can play a good role in correcting type Ⅱ respiratory failure and can effectively control the development of the disease.