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目的了解乌鲁木齐市高新区儿童麻疹抗体免疫状况,为制定免疫对策提供科学依据。方法采用整群抽样法抽取高新区6所学校3~15岁儿童共560人,采用酶联免疫法定性测定麻疹IgG抗体水平检测。结果乌鲁木齐市高新区3~15岁儿童麻疹总体抗体阳性率92.32%,其中不同年龄组、性别、民族、现居住地、免疫史、既往麻疹患病史的抗体阳性率差异均无统计学意义(P≥0.05)。麻疹患病率为1.43%。接种1剂次及2剂次疫苗者血清抗体阳性率差异无统计学意义(P≥0.05)。本市人口的抗体阳性率高于流动人口,并且随着年龄组的增高而抗体阳性率降低,差异有统计学意义(P<0.05)。结论流动儿童麻疹抗体水平有待进一步提高,开展流动儿童强化免疫是消除麻疹重要措施。
Objective To understand the immune status of measles antibody in hi-tech zones in Urumqi and provide a scientific basis for the development of immunization strategies. Methods A total of 560 children aged 3-15 years from 6 schools in the high-tech zone were sampled by cluster sampling method. The level of measles IgG antibody was detected by enzyme-linked immunosorbent assay. Results The positive rate of measles antibody in children aged 3 ~ 15 years old in Urumqi was 92.32%. There was no significant difference in the positive rate of measles antibody among different age groups, sex, ethnicity, current residence, immunization history and past measles status ( P> 0.05). The prevalence of measles was 1.43%. There was no significant difference in the positive rate of serum antibody between vaccination with 1 dose and 2 doses of vaccine (P≥0.05). The positive rate of antibody in this population was higher than that of floating population, and the antibody positive rate decreased with the increase of age group, the difference was statistically significant (P <0.05). Conclusion The measles antibody level of migrant children needs to be further improved. Intensive immunization of migrant children is an important measure to eliminate measles.